›› 2001, Vol. 44 ›› Issue (3): 366-372.

• 研究论文 • 上一篇    下一篇

杆状病毒的结构蛋白及其功能

孙国勋, 丁翠, 蔡秀玉   

  • 出版日期:2001-08-20 发布日期:2001-08-20

Structural proteins of baculovirus and their functions

SUN Guo-xun, DING Cui, CAI Xiu-yu   

  • Online:2001-08-20 Published:2001-08-20

摘要: 综述了昆虫杆状病毒的主要结构蛋白及其功能。髓核是由大约120 kb的双链DNA分子和与其密切相关的碱性蛋白所组成,碱性蛋白同DNA紧密结合以维持其复杂有序的超螺旋结构,并且能够增强杆状病毒DNA的感染性;衣壳蛋白是杆状病毒粒子的主要结构蛋白,主要有VP 39、VP 78/83、VP 87、VP 80、VP 24;囊膜蛋白有PDV-E 25、PDV-6 e、PDV-E 66、PDV-E 56、PDV-E 18、PDV-EC 27、PDV-E 35、PDV-EC 27、BV/PDV-E 26、PDV-43、gp 64-67、VP 40/41;包涵体的基质蛋白;多角体(或颗粒体)膜主要是由糖类构成,VP 32-36是与之相关的蛋白。

关键词: 杆状病毒, 结构蛋白, 功能

Abstract: Structural proteins of baculovirus and their functions are reviewed. Core of the virus is composed of supercoiled dsDNA genome proximately 120 kb in size and related basic proteins which couple with the genome DNA to maintain its complexity and enhance its infectivity. Capsid proteins are the main structural proteins of the virus, which include VP39, VP78/83, VP87, VP80 and VP24. Envelope proteins include PDV-E25, PDV-6e, PDV-E66, PDV-E56, PDV-E18, PDV-EC27, PDV-E35, PDV-EC27, BV/PDV-E26, PDV-43, gp64-67 and VP40/41. The paper also presents some other important structural proteins of the virus.

Key words: baculovirus, functions, structural proteins