›› 2003, Vol. 46 ›› Issue (5): 649-954.doi:

• 研究论文 • 上一篇    下一篇

昆虫小RNA病毒研究进展

王小纯,胡远扬,张珈敏   

  • 出版日期:2003-10-20 发布日期:2003-10-20

Advances in insect picornavirus research

WANG Xiao-Chun, HU Yuan-Yang*, ZHANG Jia-Min   

  • Online:2003-10-20 Published:2003-10-20
  • Contact: HU YuanYang

摘要: 昆虫小RNA病毒依据基因组结构特点分为家蚕软化病毒组、蟋蟀痹病毒组和豌豆蚜病毒组。昆虫小RNA病毒蛋白质翻译具有独特性:不依赖于帽子结构,不需要启始因子eIF1、eIF1A和帽子结合蛋白eIF4E;而且蟋蟀痹病毒组和豌豆蚜病毒组结构蛋白翻译从内部核糖体进入位点独立启始,启始密码子是CUU。该文还简介了昆虫小RNA病毒复制机理及与其它动、植物小RNA病毒或类小RNA病毒的亲缘关系等的研究进展。

关键词: 昆虫, 小RNA病毒, 基因组结构, 系统发育

Abstract: According to the characteristics of the genome structure of insect picornaviruses, they can be divided into three groups: infectious flacherie virus(IFV) group, cricket paralysis virus(CrPV) group and Acyrhosiphon pisum virus (APV) group. The initiation of protein translation of insect picornavirus is unique: independent of map structure, and initiation factors eIF1 and eIF1A and map combined protein eIF4E are not necessary; furthermore, the translation of capsid protein of CrPV group and APV group initiate from internal ribosome entry site and the initiation code is CUU. The paper also reviewed advances on replication mechanism of insect picornavirus and the phylogeny among insect, mammal and plant picornaviruses or icorna-like viruses.

Key words: insect, picornavirus, genome structure, phylogeny