Abstract: A preliminary study of the structural activity and relationship between EBF and its derivatives was conducted by comparing the structure of the aphid alarm pheromone (EBF) with its fluoro derivatives using computer molecular fitting. This demonstrated that these derivatives, which are substituted by one, two or three fluorine molecules in the conjugated diene of EBF, are similar to EBF in structure. They could possibly be active in bioassay.

Key words: [E]-β-farnesene, aphid alarm pheromone, fluoro derivatives, structureactivity