›› 2003, Vol. 46 ›› Issue (6): 766-772.doi:

• RESEARCH PAPERS • Previous Articles     Next Articles

Advances in insect virus synergists

GUO Hui-Fang1,2, FANG Ji-Chao1, HAN Zhao-Jun2   

  • Online:2003-12-20 Published:2003-12-20

Abstract: This paper summarized the recent advances in insect virus synergists, including the synergistic characteristics and mechanism of viral enhancin, a biological synergist from insect viruses, and the optical brightener, a chemical synergist. The paper also gave a framework of the molecular biology of enhancin. Viral enhancin was found in nuclear polyhedrosis virus, granulosis virus, cytoplasmic polyhedrosis virus and entomopoxvirus, and it was metalloproteases. Several enhancin genes have been cloned, based on that, some enhancin recombinant virus and plant has been constructed. Optical brightener with enhancing activity were stilbenes. It has been confirmed that the destruction of peritrophic membrane contributed to the enhancement of viral infectivity by synergists. Other mechanism related to the enhancement needs further study. Finally the use of insect virus synergists was discussed.

Key words: Insect virus, synergists, insect virus enhancing, optical brightener