Abstract: The effects of drugs and poisons on the growth and development of necrophagous flies is an important research direction in the field of forensic entomotoxicology. The results of these researches can correct the time of death in cases associated with drugs and poisons. With the global abuse of drugs in recent years increasing, death caused by drugs and poisons becomes more frequent. It often requires application of necrophagous flies to estimate the postmortem interval （PMI） in such cases. In order to illustrate the research advances, future focuses and difficulties of this field, this paper defined and characterized forensic entomotoxicology, and then reviewed the international research progress in recent years according to different drug and poison classification. These studies indicate that some drugs and poisons have a certain impact on the growth and development of necrophagous flies, and this impact has differences among species. At present, the research of this field is still at the stage of macro-observation. This research field is continually widening, and the existing researches are deepening. However, there are many more issues which need to be further studied and discussed.

Key words: Forensic entomology, forensic entomotoxicology, drug abuse, necrophagous flies, postmortem interval