昆虫抗菌肽和抗真菌肽结构与功能的关系及分子设计

Abstract

Abstract: Insect antimicrobial peptides (AMP), including antibacterial peptides and antifungal peptides (AFP), are classified based on the accession sequences registered in GenBank and EMBL databases, and the relationships between the molecular structure and function of cecropin family and their molecular design strategies were summarized.The research progress and the challenging problems concerning the relationships between the known molecular structure and function of some newly identified antifungal peptides were introduced and analyzed. Such information will be useful not only for the basic studies of antimicrobial peptides but also for developing novel antibiotic drugs in the near future.

Key words: Insect, antibacterial peptide, antifungal peptide, molecular design

XIAO Ye-Chen^1,4, WEN Shuo-Yang², HUANG Ya-Dong³, YANG Wan-Ying¹ , CAO Yang¹. The relationships between the structure and function of insect antibacterial peptides and antifungal peptides and molecular design[J]., 2004, 47(5): 659-669.

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The relationships between the structure and function of insect antibacterial peptides and antifungal peptides and molecular design

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