Abstract:

cDNAs of aminopeptidase N (APN) from Helicoverpa armigera (Hübner) were cloned and sequenced. One aminopeptidase N (APN1) was identified. This aminopeptidase N had 3 220 nucleotides with a 3 042 bp open reading frame that encodes 1 014 amino acids. The putative amino acid sequence shares the consensus zinc binding/gluzincin motif HEXXHX₁₈E and a hydrophobic signal sequence with 20 amino acids in Nterminal region common to all aminopeptidases， but no glycosylphosphatidylinositol (GPI) anchor signal sequence in Cterminal region of APN1 was found. The sequences reported here had been deposited in the GenBank database (Accession number: AY358034).

Key words: Helicoverpa armigera, aminopeptidase N, GPI anchor, receptor