The analogous proto-oncoproteins c-kit specially expressed in spermatocytes and sperm in postnatal spermatogenesis of Loxoblemmus doenitzi Stein were detected by immunohistochemistry. In meiosis,the analogous c-kit positive granules were on the cellular membrane of spermatocyte from metaphase Ⅰ to telophase Ⅱ. After meiosis,the analogous c-kit positive granules only existed in the head of the mature sperm in the testis and the spermatheca. The investigation indicated that the analogous proto-oncoprotein kit and its receptor as a signal transduction system may play some important role in keeping the meiosis process, the sperm maturation and the fertilization for L. doenitzi. These results are similar to those on mice which were marked by the proto-oncoproteins c-kit, but the difference still existed in some aspects. For example, there are many c-kit positive granules in mice's spermatogonium and spermatoon during spermatogenesis, but there are not the analogous c-kit positive granules in L. doenitzi's spermatogenous and spermatoon. It is so inferred that the functions of the analogous c-kit may be similar to the c-kit in regulating animal reproduction aspects. They may belong to the same gene's product.