›› 2007, Vol. 50 ›› Issue (9): 889-894.doi:

• RESEARCH PAPERS • Previous Articles     Next Articles

Immunomodulatory effects of the extract of Musca domestica larvae on irradiated mice

LIU Bin,ZHANG Ke-Tian,SHEN Si,LEI Chao-Liang,HUANG Wen   

  • Online:2007-09-20 Published:2007-10-10
  • Contact: HUANG Wen E-mail:huangwen@mail.hzau.edu.cn

Abstract: The immunomodulatory effects of the extract of housefly Musca domestica larvae on irradiated Kunming mice were studied with such indices as the viscera indices, the activity of NK cell, the proliferation of T and B lymphocyte, SOD activity and MDA content assayed. The results indicated that the treatment with the extract consecutively for 18 d increased the mice Spleen and Thymus indices, the activity of natural killer cell, and the proliferation of T, B lymphocyte. Serum analysis demonstrated that the extract significantly reduced the content of MDA and increased the activity of SOD. The results suggest that the extract of housefly larvae has positive immunomodulatory effects on mice irradiated or not

Key words: Musca domestica, larvae extract, irradiated mice, immunomodulation, antioxidation